Citrusim 250mg

-Ação antioxidante;
-Estimulo da lipólise;
-Inibição da lipogênese;
-Auxiliar no emagrecimento de peso.
 

1. Dossiê Técnico do Fabricante. 1. Kegele CS et al., A randomized trial on the effects of CitrusiM® (Citrus sinensis (L.) Osbeck dried extract) on body composition, Clinical Nutrition Experimental, https://doi.org/10.1016/j.yclnex.2019.08.002 2. Galvano F, et al. Bioavailability, antioxidant and biological properties of the natural free-radical scavengers cyanidin and related glycosides. Ann Ist Super Sanita. 2007;43(4):382-93. 3. Guo H, et al. Cyanidin 3-glucoside protects 3T3-L1 adipocytes against H2O2- or TNF-alphainduced insulin resistance by inhibiting c-Jun NH2-terminal kinase activation. Biochem Pharmacol 2008; 75:1393–1401. 4. Latado RR, et al. Accumulation of anthocyanins and characteristics of fruits of blood oranges during cold storage. Rev. Bras. Frutic. vol.30 no.3 Jaboticabal Sept. 2008. 5. Rampersaud GC. A comparison of nutrient density scores for 100% fruit juices. J Food Sci. 2007 May;72(4):S261-6. 6. Rapisarda P, et al. Hydroxycinnamic acids as markers of Italian blood orange juices. J Agric Food Chem 1998; 46: 464–470. 7. Rapisarda P. Sample preparation for vitamin C analysis of pigmented orange juices. Ital J Food Sci 1996; 251–256. 8. Ross JA, et al. Dietary flavonoids: bioavailability, metabolic effects, and safety. Annual Review of Nutrition, Palo Alto, n.22, p.19-34, 2002. 9. Salamone F, et al. Moro orange juice prevents fatty liver in mice. World J Gastroenterol. 2012 Aug 7;18(29):3862-8. 10. Takikawa M, et al. Dietary anthocyanin-rich bilberry extract ameliorates hyperglycemia and insulin sensitivity via activation of AMP-activated protein kinase in diabetic mice. J Nutr. 2010 Mar;140(3):527-33. 11. Titta L, et al. Blood orange juice inhibits fat accumulation in mice. Int J Obes (Lond). 2010 Mar;34(3):578-88. 12. Tsuda T, et al. Anthocyanin enhances adipocytokine secretion and adipocyte-specific gene expression in isolated rat adipocytes. Biochem Biophys Res Commun. 2004 Mar 26;316(1):149-57. 13. Tsuda T, et al. Dietary cyanidin 3-O-beta-D-glucoside-rich purple corn color prevents obesity and ameliorates hyperglycemia in mice. J Nutr. 2003 Jul;133(7):2125-30. 14. Tsuda T, et al. Microarray profiling of gene expression in human adipocytes in response to anthocyanins. Biochem Pharmacol 2006; 71: 1184–1197. 15. Tsuda T. Regulation of adipocyte function by anthocyanins; possibility of preventing the metabolic syndrome. J Agric Food Chem 2008; 56: 642–646. 16. Fiore A, et al. Antioxidant activity of pasteurized and sterilized commercial red orange juices. Mol Nutr Food Res. 2005 Dec;49(12):1129-35. 17. Omdamiro O, et al. Evaluation of anti-inflamatory, antibacterial and antioxidant properties of ethanolic extracts of Citrus sinensis peel and leaves. Journal of Chemical and Pharmaceutica Research, v.5, n. 5, 2013.

Contraindicações / Precauções: Gestantes, lactantes e crianças (com menos de 6 anos de idade), pacientes que sofram de gastrite, ulceras gastroduodenais, síndrome do colon irritável, colite ulcerosa, doenças de Chron, afecções hepáticas, doença de Parkinson ou outras enfermidades neurológicas.
 

Citrusim.................................250mg
Excipiente padrão q.s.p........1mg
(Dose para 1 cápsula)
 

Tomar 1 cápsula 2x ao dia ou conforme orientação do profissional habilitado.